ComM is a hexameric helicase that promotes branch migration during natural transformation in diverse Gram-negative species
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RuvAB-mediated branch migration does not involve extensive DNA opening within the RuvB hexamer
The Escherichia coli RuvA and RuvB proteins promote the branch migration of Holliday junctions during the late stages of homologous recombination and DNA repair (reviewed in [1]). Biochemical and structural studies of the RuvAB-Holliday junction complex have shown that RuvA binds directly to the Holliday junction [2] [3] [4] [5] [6] and acts as a specificity factor that promotes the targeting o...
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